Problem skin

PICOgenesis

An advanced laser that delivers ultra-short pulses to break down pigment without damaging the surrounding skin. Combined with rose plant exosomes, it gives a brighter, more even complexion over time.

What it treats

Sun spots, lentigines, PIH, and true brown pigmentMelasma or mixed pigment when part of a structured plan and strict sun protectionPost-acne scarring and marksDull, tired skinUneven tone and clarity*It does not treat redness or inflammation*
PICOgenesis at Harmony Medical
Best resultsA course, at least 5 sessions
Procedure time10 to 20 minutes
DowntimeAbout 24 hours
Cost£395, or 5 for £1,800

The Clinical Protocol

Phase 01
Cleanse and skin scan

Your skin is cleansed and a skin scan is performed.

Phase 02
The laser pass

The handpiece is passed over the area. You feel a gentle warm flickering.

Phase 03
Quick and comfortable

It takes about 10 to 20 minutes.

Phase 04
Exosomes applied

Exosomes are gently applied into the skin.

Before & after

PICOgenesis ultrasound colour Doppler result 1 at Harmony Medical
Before & after

Real Harmony Medical patients, shared with consent. Individual results vary.

Questions, answered

Reducing post-acne scarring and marks, brightening dull skin, and evening out tone and clarity.

Usually minimal, around 24 hours of mild redness, warmth or a light full feeling.

Pico works best as a course of at least 5 sessions, with the number depending on your concern.

Please leave the exosomes on for at least 6 hours before washing them off.

Pico Laser & Exosomes:
• Breaks down pigment so your body clears it naturally, without thinning the skin.
• Rose exosomes calm the skin and lower the risk of flare-ups and post-inflammatory pigmentation (PIH).
• Improves overall tone, texture, clarity, and barrier strength at the same time.
• Treats pigment at the source for more stable results and lower relapse risk.

Hydroquinone:
• Works only on the surface and only targets pigment.
• Can thin or irritate the skin, especially in darker or reactive skin types.
• Pigment often rebounds and relapses when discontinued.

Pico delivers ultra-short pulses of energy creating a photoacoustic effect (sound into energy) that breaks pigment without heat-damage. The laser does not cut the skin, so downtime is minimal (approx 24 hours of mild redness, warmth or tingling). Your immune system clears the fragments over the following weeks.

Right after Pico, the skin is most responsive to repair. We apply rose plant-derived exosomes post-laser at every visit to calm pigment flaring, reduce redness, shorten recovery, and support a stronger skin barrier.

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